I have been on Zoloft for depression for a few months now (I had tried about 10 different medications in the last few years until I found one my body accepted and worked with) and I was also prescribed ambien since I can't sleep at night, and Klonopin because I panic at night as well. I started taking .5 mgs and now I am up to 2 mgs a night of Klonopin. I try not to take it every night but I am not able to relax enough to get to sleep on the nights I don't take it. My body has built up a tolerance to the ambien as well. I can take 5 or 10 mgs one night and finally get some sleep.. but the next night I can take 10 mgs of ambien again and be up till 6AM. I have even tried 10 mgs of ambien and 1 mg of Klonopin together (My dr said I could try that..) and even that wouldn't relax me enough to sleep because I had taken ambien the night before. Has anyone found an anti-anxiety drug that helps as much as Klonopin does but you don't have to increase the dose each night in order to feel the same effects?