Congratulations on finding the right drug to improve your life. The sense of relief you must feel must be wonderful. Inspiring to hear that you never gave up and were willing to keep trying to make improvements.

larry1888 Join the community Huntington, WV #f1 1 min ago I read on the web about a man who had treatment-resistant clinical depression for six years, and after trying everything else that didn't work, ANAFRANIL brought him out of it. He said for him it was a miracle drug that gave him his life back. I've been in major depression for over three years. You name it, I tried it--even ECT, TMS, and every SSRI, without results. I also have OCD, which is what anafranil is usually prescribed for. The thing is, you have to take at least 100 mgs/day, and it takes a good three months for it to work. It brings you out of it gradually, over a period of a couple weeks. It's quick enough to notice it, though. Its side effecta are dry mouth and some weight gain (for me that was a good thing--it brought me up to my normal weight--I had lost as much as 25 lbs during my three year episode. Another thing is, you probably will feel a bit worse at first, and it does actually take 2-3 months or slightly longer to kick in, but when it does, you know it. My thinking cleared up and I was able to learn, laugh, and be happy again. If you're desperate to get better, and you've failed to respond to the normal antidepressants, I would recommend this regimen to you! It's worth the wait. The odd thing with me, is that this OCD drug didn't stop my OCD (which is just a minor inconvenience to me), but depression was terrible, and I'm convinced it would have gone on for the rest of my life, had I not intervened with this. I had even discussed having deep brain stimulation or gamma-knife brain surgery with my psychiatrist, who felt that I might have to resort to one of those invasive techniques. I met with a psychiatrist at the Cleveland Clinic, who recommended anafranil for me, at the strength of 100 mgs a day. I wanted DBS, but he said they wouldn't do it without trying and failing on OCD treatment. The ironic thing is, my depression is gone, but my OCD symptoms are still here: hand- washing, counting, teeth brushing, and so forth, but as I said the OCD for me was just a mild inconvenience and still is, but my awful terrible major depression is gone. Just like that.