My best friend is fighting to come out of clinical depression. Her family has turned away and I'm all she has. She is also starting treatment for the Hepatitis C virus, which in itself may lead to depression. I am woefully unprepared and need guidance on how to help her through this. I can't replace the people she loves and don't give her the time of day. If I call her or knock on her door, she wants to be alone. If I don't call her, she gets upset because I should have known to call her. I understand these are symptoms. But I don't know how to deal with them. I have joined this site hoping the healthcare professionals and other sufferers of depression can guide me. Please, whatever input you can give me will be greatly appreciated.