I had some relief from depression when the doctor added Wilburton (bupropion) to the fluoxetine that I have been taking for years. Had great luck with the fluoxetine till recently. While I felt less depressed when Wilburton was added,it did nothing for my chronic pain. Naturally chronic paid can cause depression. Today is my first day to take Cymbalta. Sure hope it helps because I would love to be less depressed about the pain. Cymbalta is supposed to be useful for people with fibromyalgia, hoping that it will be useful for tendonitis and bursitis.