I have been on Wellbutrin (twice daily) and it has not been working for me. I changed to Wellbutrin XL (times release). Does anyone know the difference? I tried it before, however, it was at the same time they took me off Klonopin way too fast and I was going through major withdrawals. It was awful. I have been really depressed and I can't seem to get out of it. I am exhausted all the time, overwhelmed, can not concentrate, weight gain. I feel terrible, not to mention, I just feel like crying all the time. The good thing is......no one at work would ever have any idea that I am so depressed. I seem like the happiest person at work, then I come home and collapse.