I know Wellbutrin has a lower seizure threshold than most other meds and there are certain criteria which make some people more prone to having a seizure than others. However, I've been taking Wellbutrin (bupropion, at 450mg/day) for years now (5 years at least) and have never had a seizure. Recently my pdoc raised the dose to 500mg/day and wants to eventually increase it to 600mg/day. Bupropion is the only med I take; personally I can't stand the SSRIs' side-effects.
The med search can be frustrating...I've been on at least 9 other meds besides buproprion...sometimes only taking one, sometimes in combination. Bupriopion is the only med that has helped control my depression while manifesting very few side effects. The only negative side effect I experience is dry mouth; I've also lost over 10 lbs since increasing my dosage 50/mg....I like that side effect!
Good luck in your med search.
Isil'zha veni
