Can anyone give me any info on taking wellbutrin with prozac? I use to take prozac 20mg a day, then found it wasn't working that well anymore so I switched to wellbutrin. Wellbutrin I thought was working but I started getting really irritable, having anxiety attacks again and just overall not myself. Went to see the pysch dr for the first time Friday and he tells me I suffer from depression, anxiety and ocd and recommended I try taking 20mg of prozac with the 300 mg wellbutrin xl. If you had any experiences, good or bad with this combo, I would appreciate your feedback.