Hi all,I was wonering if anyone can help me,? I have been on amytriptylene 75mg for over twenty years, a new dr came along and said that wasnt enough to treat my depression, she has increased it to 200mg at night it is only three weeks ago,will it still take a good few weeks to start working as a new theraputic dose? I am going through a particularly bad time, I do get like this and then I eventually come back up,its a very lonely time I wish I could just feel that little bit better,I want to relax but Im finding it hard, I am sleeping very well,In some ways I wish I could have had this dr long ago, shes very reassuring anyway, I would appreciate any advice from anyone who might be able to help. thankyou cadge