This post will tell you a bit more about the symptoms of Major depressive Disorder.
Major depressive disorder (MDD) is the most common form of mood disorder. During an episode of MDD the world is seen through a kind of dark filter. You feel extremely sad, full of self-doubt, doom and gloom and the environment seems overwhelming, imposing and full of obstacles. To individuals experiencing depression, the world seems hopeless with little or no possibility of reprieve; this can tragically lead some to consider suicide as their only outlet.
Depressives interpret and view the world differently than those who are not depressed, which tends to feed and confirm their negative self-image. Normal events such as calling a friend and the call not being returned can be misinterpreted, overgeneralized and catastrastized to the extend that the individual believes that their friend no longer likes them or wants to associate with them.